SGPP1, sphingosine-1-phosphate phosphatase 1

SGPP1, sphingosine-1-phosphate phosphatase 1

• Sphingosine-1-phosphate (S1P) is a bioactive sphingolipid metabolite that regulates diverse biologic processes. SGPP1 catalyzes the degradation of S1P via salvage and recycling of sphingosine into long-chain ceramides (Mandala et al., 2000 [PubMed 10859351]; Le Stunff et al., 2007 [PubMed 17895250]).[supplied by OMIM, Jun 2009]

• Gene Synonyms (sphingosine-1-phosphate phosphatase 1, hSPP1, hSPPase1, sphingosine-1-phosphatase 1, sphingosine-1-phosphate phosphohydrolase 1, spp1, SPP-1, SPPase1,)
• NCBI Gene ID: 81537
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9BX95
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

sphingosine-1-phosphate phosphatase 1 interacts with:

• adhesion G protein-coupled receptor G5
  glycerophosphodiester phosphodiesterase domain containing 5
  ras homolog family member T2
  solute carrier family 22 member 9
  TM2 domain containing 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.