PPP1R3C, protein phosphatase 1 regulatory subunit 3C

PPP1R3C, protein phosphatase 1 regulatory subunit 3C

• This gene encodes a carbohydrate binding protein that is a subunit of the protein phosphatase 1 (PP1) complex. PP1 catalyzes reversible protein phosphorylation, which is important in a wide range of cellular activities. The encoded protein affects glycogen biosynthesis by activating glycogen synthase and limiting glycogen breakdown by reducing glycogen phosphorylase activity. DNA hypermethylation of this gene has been found in colorectal cancer patients. The encoded protein also interacts with the laforin protein, which is a protein tyrosine phosphatase implicated in Lafora disease. [provided by RefSeq, Sep 2016]

• Gene Synonyms (protein phosphatase 1 regulatory subunit 3C, PP1 subunit R5, Phosphatase 1, regulatory inhibitor subunit 5, protein phosphatase 1 regulatory subunit 5, protein phosphatase 1, regulatory (inhibitor) subunit 3C, protein targeting to glycogen, PPP1R5, PTG,)
• NCBI Gene ID: 5507
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UQK1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 1 regulatory subunit 3C interacts with:

• actin beta like 2
  aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
  early endosome antigen 1
  EPM2A glucan phosphatase, laforin
  lacritin
  latexin
  LIM domain and actin binding 1
  LON peptidase N-terminal domain and ring finger 1
  NHL repeat containing E3 ubiquitin protein ligase 1
  protein phosphatase 1 regulatory subunit 3D
  small glutamine rich tetratricopeptide repeat containing alpha
  starch binding domain 1
  thioredoxin reductase 2
  tropomyosin 4

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.