TRMT12, tRNA methyltransferase 12 homolog

TRMT12, tRNA methyltransferase 12 homolog

• Wybutosine (yW) is a hypermodified guanosine at the 3-prime position adjacent to the anticodon of phenylalanine tRNA that stabilizes codon-anticodon interactions during decoding on the ribosome. TRMT12 is the human homolog of a yeast gene essential for yW synthesis (Noma and Suzuki, 2006).[supplied by OMIM, Mar 2008]

• Gene Synonyms (tRNA wybutosine-synthesizing protein 2 homolog, alpha-amino-alpha-carboxypropyl transferase TYW2, homolog of yeast tRNA methyltransferase, tRNA methyltranferase 12 homolog, tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase, tRNA-yW-synthesizing protein 2, TRM12, TYW2,)
• NCBI Gene ID: 55039
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q53H54
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

tRNA methyltransferase 12 homolog interacts with:

• ligand of numb-protein X 1
  PR/SET domain 6
  zinc finger protein 556

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.