PPP2R3C, protein phosphatase 2 regulatory subunit B''gamma

PPP2R3C, protein phosphatase 2 regulatory subunit B''gamma

• This gene encodes a regulatory subunit of the serine/threonine phosphatase, protein phosphatase 2. This protein is localized to both nuclear and cytoplasmic regions depending on cell cycle phase. Homozygous conditional knockout mice for this gene exhibit reduced numbers and impaired proliferation of immune system B cells. This protein may regulate the expression of the P-glycoprotein ATP-binding cassette transporter through its phosphatase activity. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Feb 2015]

• Gene Synonyms (serine/threonine-protein phosphatase 2A regulatory subunit B'' subunit gamma, protein phosphatase 2 (formerly 2A), regulatory subunit B'', protein phosphatase 2, regulatory subunit B'', gamma, protein phosphatase subunit G5PR, rhabdomyosarcoma antigen MU-RMS-40.6A, rhabdomyosarcoma antigen Mu-RMS-40.6C, C14orf10, G4-1, G5pr, GDRM, SPGF36,)
• NCBI Gene ID: 55012
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q969Q6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 2 regulatory subunit B''gamma interacts with:

• centrosomal protein 128
  centrosomal protein 19
  centrosomal protein 350
  centrosomal protein 43
  centrosomal protein 72
  CKLF like MARVEL transmembrane domain containing 5
  coiled-coil domain containing 146
  coiled-coil domain containing 33
  coiled-coil domain containing 77
  developmental pluripotency-associated 3
  dynein cytoplasmic 2 heavy chain 1
  enkurin domain containing 1
  FAM161 centrosomal protein A
  FAM161 centrosomal protein B
  modulator of apoptosis 1
  NCBP2 antisense 2 (head to head)
  SMG9 nonsense mediated mRNA decay factor
  VPS50 subunit of EARP/GARPII complex

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.