LEPROT, leptin receptor overlapping transcript

LEPROT, leptin receptor overlapping transcript

• LEPROT is associated with the Golgi complex and endosomes and has a role in cell surface expression of growth hormone receptor (GHR; MIM 600946) and leptin receptor (OBR, or LEPR; MIM 601007), thereby altering receptor-mediated cell signaling (Couturier et al., 2007 [PubMed 18042720]; Touvier et al., 2009 [PubMed 19907080]).[supplied by OMIM, Jul 2010]

• Gene Synonyms (leptin receptor gene-related protein, DnaJ (Hsp40) homolog, subfamily C, member 6, OB-R gene-related protein, endospanin, endospanin-1, leptin receptor overlapping transcript protein, LEPR, OB-RGRP, OBRGRP, VPS55,)
• NCBI Gene ID: 54741
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A087X0N2
  UNIPROT ID#>>O15243
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

leptin receptor overlapping transcript interacts with:

• core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1
  phospholipid phosphatase related 1
  transmembrane protein 120A

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.