C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

C1GALT1, core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1

• The protein encoded by this gene generates the common core 1 O-glycan structure, Gal-beta-1-3GalNAc-R, by the transfer of Gal from UDP-Gal to GalNAc-alpha-1-R. Core 1 is a precursor for many extended mucin-type O-glycans on cell surface and secreted glycoproteins. Studies in mice suggest that this gene plays a key role in thrombopoiesis and kidney homeostasis.[provided by RefSeq, Sep 2010]

• Gene Synonyms (C1GALT, T-synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1, B3Gal-T8, core 1 O-glycan T-synthase, core 1 UDP-galactose:N-acetylgalactosamine-alpha-R beta 1,3-galactosyltransferase 1, core 1 beta3-Gal-T1, epididymis secretory sperm binding protein,)
• NCBI Gene ID: 56913
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9NS00
  UNIPROT ID#>>A0A024RA32
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

core 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1 interacts with:

• ADP ribosylation factor like GTPase 13B
  ankyrin repeat and sterile alpha motif domain containing 6
  complexin 4
  family with sequence similarity 209 member A
  family with sequence similarity 210 member B
  G protein-coupled receptor 101
  G protein-coupled receptor 151
  glutathione peroxidase 8 (putative)
  leucine rich repeat containing 15
  leucine twenty homeobox
  LHFPL tetraspan subfamily member 5
  reticulophagy regulator family member 3
  solute carrier family 7 member 14
  transmembrane protein 14B
  transmembrane protein 237
  transmembrane protein 52B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.