NSDHL, NAD(P) dependent steroid dehydrogenase-like

NSDHL, NAD(P) dependent steroid dehydrogenase-like

• The protein encoded by this gene is localized in the endoplasmic reticulum and is involved in cholesterol biosynthesis. Mutations in this gene are associated with CHILD syndrome, which is a X-linked dominant disorder of lipid metabolism with disturbed cholesterol biosynthesis, and typically lethal in males. Alternatively spliced transcript variants with differing 5' UTR have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (sterol-4-alpha-carboxylate 3-dehydrogenase, decarboxylating, epididymis secretory sperm binding protein, protein H105e3, short chain dehydrogenase/reductase family 31E, member 1, H105E3, SDR31E1, XAP104,)
• NCBI Gene ID: 50814
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q15738
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NAD(P) dependent steroid dehydrogenase-like interacts with:

• 5-hydroxytryptamine receptor 3C
  arginyl-tRNA synthetase 2, mitochondrial
  cyclin L2
  EvC ciliary complex subunit 2
  forkhead box I2
  OTU deubiquitinase with linear linkage specificity like
  pleckstrin homology domain containing A4
  rhomboid 5 homolog 2
  rhomboid domain containing 1
  synoviolin 1
  tectonic family member 2
  thioredoxin related transmembrane protein 2
  transmembrane protein 17
  transmembrane protein 216
  transmembrane protein 30A
  transmembrane protein 31
  ubiquitin specific peptidase 47

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.