- Gene Overview
- Interaction Network
- Sequence Verification
NT5C, 5', 3'-nucleotidase, cytosolic
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This gene encodes a nucleotidase that catalyzes the dephosphorylation of the 5' deoxyribonucleotides (dNTP) and 2'(3')-dNTP and ribonucleotides, but not 5' ribonucleotides. Of the different forms of nucleotidases characterized, this enzyme is unique in its preference for 5'-dNTP. It may be one of the enzymes involved in regulating the size of dNTP pools in cells. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Nov 2011]
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Gene Synonyms (5'(3')-deoxyribonucleotidase, cytosolic type, 5' nucleotidase, deoxy (pyrimidine), cytosolic type C, cytosolic 5',3'-pyrimidine nucleotidase, deoxy-5'-nucleotidase 1, epididymis luminal protein 74, epididymis secretory sperm binding protein, uridine 5'-monophosphate phosphohydrolase 2, uridine 5-prime monophosphate hydrolase 2, DNT, DNT1, HEL74, P5N2, PN-I, PN-II, UMPH2, cdN, dNT-1,)
- NCBI Gene ID:
30833
- Species:
Homo sapiens (Human)
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UNIPROT ID#>>Q8TCD5
UNIPROT ID#>>V9HWF3
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for this Gene »
Gene products are often involved in multiple pathways and networks within a living
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5', 3'-nucleotidase, cytosolic interacts with:
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