OSTM1, osteoclastogenesis associated transmembrane protein 1

OSTM1, osteoclastogenesis associated transmembrane protein 1

• This gene encodes a protein that may be involved in the degradation of G proteins via the ubiquitin-dependent proteasome pathway. The encoded protein binds to members of subfamily A of the regulator of the G-protein signaling (RGS) family through an N-terminal leucine-rich region. This protein also has a central RING finger-like domain and E3 ubiquitin ligase activity. This protein is highly conserved from flies to humans. Defects in this gene may cause the autosomal recessive, infantile malignant form of osteopetrosis. [provided by RefSeq, Jul 2008]

• Gene Synonyms (osteopetrosis-associated transmembrane protein 1, CLCN7 accessory beta subunit, GAIP-interacting protein N terminus, chloride channel 7 beta subunit, grey-lethal osteopetrosis, osteopetrosis associated transmembrane protein 1, GIPN, GL, HSPC019, OPTB5,)
• NCBI Gene ID: 28962
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86WC4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

osteoclastogenesis associated transmembrane protein 1 interacts with:

• baculoviral IAP repeat containing 7
  family with sequence similarity 177 member A1

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