MAGEA2B, MAGE family member A2B

MAGEA2B, MAGE family member A2B

• This gene is a member of the MAGEA gene family. The members of this family encode proteins with 50 to 80% sequence identity to each other. The promoters and first exons of the MAGEA genes show considerable variability, suggesting that the existence of this gene family enables the same function to be expressed under different transcriptional controls. The MAGEA genes are clustered at chromosomal location Xq28. They have been implicated in some hereditary disorders, such as dyskeratosis congenita. This gene has two identical copies at different loci. [provided by RefSeq, Jul 2008]

• Gene Synonyms (melanoma-associated antigen 2, MAGE-2 antigen, cancer/testis antigen 1.2, melanoma antigen 2, melanoma antigen family A, 2B, melanoma antigen family A2B, melanoma antigen, family A, 2, copy b, CT1.2, MAGE2,)
• NCBI Gene ID: 266740
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P43356
  UNIPROT ID#>>A0A024RC17
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

MAGE family member A2B interacts with:

• ankyrin repeat domain 45
  centrosomal protein 57 like 1
  prolyl 4-hydroxylase subunit alpha 3

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.