ZBTB20, zinc finger and BTB domain containing 20

ZBTB20, zinc finger and BTB domain containing 20

• This gene, which was initially designated as dendritic cell-derived BTB/POZ zinc finger (DPZF), belongs to a family of transcription factors with an N-terminal BTB/POZ domain and a C-terminal DNA-bindng zinc finger domain. The BTB/POZ domain is a hydrophobic region of approximately 120 aa which mediates association with other BTB/POZ domain-containing proteins. This gene acts as a transcriptional repressor and plays a role in many processes including neurogenesis, glucose homeostasis, and postnatal growth. Mutations in this gene have been associated with Primrose syndrome as well as the 3q13.31 microdeletion syndrome. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Feb 2017]

• Gene Synonyms (zinc finger and BTB domain-containing protein 20, BTB/POZ zinc finger protein DPZF, dendritic cell-derived BTB/POZ zinc finger, zinc finger protein 288, DPZF, HOF, ODA-8S, PRIMS, ZNF288,)
• NCBI Gene ID: 26137
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9HC78
  UNIPROT ID#>>B2RCW4
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

zinc finger and BTB domain containing 20 interacts with:

• anillin actin binding protein
  calmodulin-like 3
  chromodomain helicase DNA binding protein 7
  LIM domain and actin binding 1
  LIM domain and actin binding 1
  myosin XIX

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.