NDUFAF3, NADH:ubiquinone oxidoreductase complex assembly factor 3

NDUFAF3, NADH:ubiquinone oxidoreductase complex assembly factor 3

• This gene encodes a mitochondrial complex I assembly protein that interacts with complex I subunits. Mutations in this gene cause mitochondrial complex I deficiency, a fatal neonatal disorder of the oxidative phosphorylation system. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2009]

• Gene Synonyms (NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 3, NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 3, NADH dehydrogenase (ubiquinone) complex I, assembly factor 3, nuclear protein E3-3, 2P1, C3orf60, E3-3, MC1DN18,)
• NCBI Gene ID: 25915
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A4FU71
  UNIPROT ID#>>Q9BU61
  UNIPROT ID#>>Q9Y3Z0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NADH:ubiquinone oxidoreductase complex assembly factor 3 interacts with:

• acyl-CoA dehydrogenase family member 9
  angiotensin II receptor associated protein
  calcium binding protein 2
  centrosomal protein 76
  chromosome 15 open reading frame 48
  coenzyme Q9
  cysteine rich tail 1
  cytochrome c oxidase assembly factor 4 homolog
  ECSIT signaling integrator
  egl-9 family hypoxia inducible factor 3
  FAD dependent oxidoreductase domain containing 2
  golgin A6 family like 9
  inhibitor of CDK, cyclin A1 interacting protein 1
  intraflagellar transport 122
  keratin 27
  keratin associated protein 10-3
  leucine rich repeat kinase 2
  limb development membrane protein 1 like
  LSM1 homolog, mRNA degradation associated
  methyl-CpG binding domain protein 3 like 1
  mitochondrial ribosomal protein S21
  NADH:ubiquinone oxidoreductase complex assembly factor 1
  NADH:ubiquinone oxidoreductase complex assembly factor 4
  NADH:ubiquinone oxidoreductase complex assembly factor 5
  NADH:ubiquinone oxidoreductase core subunit S7
  NADH:ubiquinone oxidoreductase subunit A13
  NADH:ubiquinone oxidoreductase subunit B11
  ring finger protein 123
  ring finger protein 146
  TP53 regulated inhibitor of apoptosis 1
  translocase of inner mitochondrial membrane domain containing 1
  U2AF homology motif kinase 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.