FTSJ1, FtsJ RNA 2'-O-methyltransferase 1

FTSJ1, FtsJ RNA 2'-O-methyltransferase 1

• This gene encodes a member of the methyltransferase superfamily. The encoded protein localizes to the nucleolus, binds to S-adenosylmethionine, and may be involved in the processing and modification of ribosomal RNA. Mutations in this gene are associated with cognitive disability. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

• Gene Synonyms (putative tRNA (cytidine(32)/guanosine(34)-2'-O)-methyltransferase, 2'-O-ribose RNA methyltransferase TRM7 homolog, FtsJ RNA methyltransferase homolog 1, FtsJ-like protein 1, cell division protein, putative ribosomal RNA methyltransferase 1, rRNA (uridine-2'-O-)-methyltransferase, tRNA methyltransferase 7 homolog, CDLIV, JM23, MRX44, MRX9, SPB1, TRMT7,)
• NCBI Gene ID: 24140
• Species: Homo sapiens (Human)
• UNIPROT ID#>>B7Z4K4
  UNIPROT ID#>>Q9UET6
  UNIPROT ID#>>B3KN91
  UNIPROT ID#>>A0A024QYX5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

FtsJ RNA 2'-O-methyltransferase 1 interacts with:

• DDB1 and CUL4 associated factor 13
  G protein nucleolar 3 like
  inhibitor of Bruton tyrosine kinase
  mitochondrial rRNA methyltransferase 1
  pleckstrin homology domain containing A4
  ribosomal protein S19 binding protein 1
  Sad1 and UNC84 domain containing 2
  sirtuin 6
  transmembrane protein 17
  ubiquitin specific peptidase 43
  ZFP91 zinc finger protein, atypical E3 ubiquitin ligase

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.