PPP1R15A, protein phosphatase 1 regulatory subunit 15A

PPP1R15A, protein phosphatase 1 regulatory subunit 15A

• This gene is a member of a group of genes whose transcript levels are increased following stressful growth arrest conditions and treatment with DNA-damaging agents. The induction of this gene by ionizing radiation occurs in certain cell lines regardless of p53 status, and its protein response is correlated with apoptosis following ionizing radiation. [provided by RefSeq, Jul 2008]

• Gene Synonyms (protein phosphatase 1 regulatory subunit 15A, growth arrest and DNA damage-inducible protein GADD34, growth arrest and DNA-damage-inducible 34, myeloid differentiation primary response protein MyD116 homolog, protein phosphatase 1, regulatory (inhibitor) subunit 15A, GADD34,)
• NCBI Gene ID: 23645
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O75807
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein phosphatase 1 regulatory subunit 15A interacts with:

• BBX high mobility group box domain containing
  CUE domain containing 2
  cullin associated and neddylation dissociated 1
  misshapen like kinase 1
  pleckstrin homology domain containing A1
  PWWP domain containing 3A, DNA repair factor
  zinc finger protein 512B
  zinc finger protein 92

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.