ATP1B4, ATPase Na+/K+ transporting family member beta 4

ATP1B4, ATPase Na+/K+ transporting family member beta 4

• This gene has been found in all vertebrate genomes sequenced to date. However, this gene has undergone a change in function in placental mammals compared to other species. Specifically, in fish, avian, and amphibian species, this gene encodes plasma membrane-bound beta-subunits of Na,K-ATPase. In placental mammals, the encoded protein interacts with the nuclear transcriptional coregulator SKIP and may be involved in the regulation of TGF-beta signaling. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2010]

• Gene Synonyms (protein ATP1B4, ATPase, Na+/K+ transporting, beta 4 polypeptide, BetaM, Na,K-ATPase beta m-subunit, X,K-ATPase beta-m subunit, x/potassium-transporting ATPase subunit beta-m,)
• NCBI Gene ID: 23439
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UN42
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATPase Na+/K+ transporting family member beta 4 interacts with:

• chondroitin sulfate N-acetylgalactosaminyltransferase 2
  chromosome 3 open reading frame 52
  contactin associated protein family member 3
  ectonucleoside triphosphate diphosphohydrolase 7
  endoplasmic reticulum metallopeptidase 1
  ER membrane protein complex subunit 3
  galactosidase beta 1 like 2
  inositol 1,4,5-trisphosphate receptor interacting protein
  lipase maturation factor 1
  lipase maturation factor 2
  myogenesis regulating glycosidase (putative)
  neurexophilin and PC-esterase domain family member 3
  out at first homolog
  post-glycosylphosphatidylinositol attachment to proteins 6
  post-GPI attachment to proteins inositol deacylase 1
  protein O-mannosyltransferase 2
  semaphorin 4C
  signal peptide peptidase like 2B
  small integral membrane protein 3
  thioredoxin domain containing 15
  thioredoxin related transmembrane protein 4
  transmembrane protein 59 like
  transmembrane protein 67

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.