ANKLE2, ankyrin repeat and LEM domain containing 2

ANKLE2, ankyrin repeat and LEM domain containing 2

• This gene encodes a member of the LEM family of inner nuclear membrane proteins. The encoded protein functions as a mitotic regulator through postmitotic formation of the nuclear envelope. Mutations in this gene cause morphology defects in the nuclear envelope and BAF hyperphosphorylation. [provided by RefSeq, Mar 2014]

• Gene Synonyms (KIAA0692, LEMD7, Lem4, MCPH16, ankyrin repeat and LEM domain-containing protein 2, LEM domain containing 7, LEM domain-containing protein 4,)
• NCBI Gene ID: 23141
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86XL3
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ankyrin repeat and LEM domain containing 2 interacts with:

• anti-silencing function 1A histone chaperone
  ATPase H+ transporting V0 subunit a2
  egl-9 family hypoxia inducible factor 3
  EvC ciliary complex subunit 2
  growth hormone inducible transmembrane protein
  inner membrane protein, mitochondrial
  interleukin 17 receptor B
  kinesin family member 26B
  limb development membrane protein 1 like
  M-phase phosphoprotein 8
  OTU deubiquitinase with linear linkage specificity like
  peptidyl-tRNA hydrolase 2
  pleckstrin homology domain containing A4
  protein phosphatase 2, regulatory subunit A, alpha
  regulator of telomere elongation helicase 1
  rhomboid 5 homolog 2
  rhomboid domain containing 1
  SH3 and cysteine rich domain 3
  synoviolin 1
  tectonic family member 3
  TNFAIP3 interacting protein 2
  transmembrane protein 17
  transmembrane protein 216
  vir like m6A methyltransferase associated
  zinc finger protein 512B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.