TNIK, TRAF2 and NCK interacting kinase

TNIK, TRAF2 and NCK interacting kinase

• Wnt signaling plays important roles in carcinogenesis and embryonic development. The protein encoded by this gene is a serine/threonine kinase that functions as an activator of the Wnt signaling pathway. Mutations in this gene are associated with an autosomal recessive form of cognitive disability. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jul 2017]

• Gene Synonyms (MRT54, TRAF2 and NCK-interacting protein kinase,)
• NCBI Gene ID: 23043
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UKE5
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

TRAF2 and NCK interacting kinase interacts with:

• ATP/GTP binding protein 1
  BICD cargo adaptor 2
  centrosomal protein 63
  DISC1 scaffold protein
  Gse1 coiled-coil protein
  hook microtubule tethering protein 1
  interleukin 20 receptor subunit alpha
  kelch repeat and BTB domain containing 7
  microtubule actin crosslinking factor 1
  mitochondrial ribosomal protein S11
  pleckstrin homology domain containing A4
  protein phosphatase 1 regulatory subunit 13B
  SMAD specific E3 ubiquitin protein ligase 1
  sorting nexin 6
  spectrin repeat containing nuclear envelope protein 1
  TGF-beta activated kinase 1 (MAP3K7) binding protein 2
  TIAM Rac1 associated GEF 2
  TRAF2 and NCK interacting kinase
  transmembrane protein 17
  tripartite motif containing 2
  vir like m6A methyltransferase associated
  WW and C2 domain containing 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.