NCBP2, nuclear cap binding protein subunit 2

NCBP2, nuclear cap binding protein subunit 2

• The product of this gene is a component of the nuclear cap-binding protein complex (CBC), which binds to the monomethylated 5' cap of nascent pre-mRNA in the nucleoplasm. The encoded protein has an RNP domain commonly found in RNA binding proteins, and contains the cap-binding activity. The CBC promotes pre-mRNA splicing, 3'-end processing, RNA nuclear export, and nonsense-mediated mRNA decay. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008]

• Gene Synonyms (CBC2, CBP20, NIP1, PIG55, nuclear cap-binding protein subunit 2, 20 kDa nuclear cap-binding protein, NCBP 20 kDa subunit, NCBP interacting protein 1, cell proliferation-inducing gene 55 protein, nuclear cap binding protein subunit 2, 20kD, nuclear cap binding protein subunit 2, 20kDa,)
• NCBI Gene ID: 22916
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P52298
  UNIPROT ID#>>B3KSB0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

nuclear cap binding protein subunit 2 interacts with:

• ADP-ribosylserine hydrolase
  autophagy related 16 like 1
  coiled-coil domain containing 8
  cullin associated and neddylation dissociated 1
  F-box and WD repeat domain containing 8
  interactor of little elongation complex ELL subunit 1
  karyopherin subunit alpha 6
  La ribonucleoprotein 7, transcriptional regulator
  leucine zipper tumor suppressor 2
  leukocyte receptor cluster member 1
  lin-28 homolog A
  lin-28 homolog B
  Mtr4 exosome RNA helicase
  myosin heavy chain 7B
  NCBP2 antisense 2 (head to head)
  phosphorylated adaptor for RNA export
  pleckstrin homology domain containing A4
  PPARG related coactivator 1
  ring finger and CCCH-type domains 1
  ring finger and CCCH-type domains 2
  SMG1 nonsense mediated mRNA decay associated PI3K related kinase
  SUZ12 polycomb repressive complex 2 subunit
  threonyl-tRNA synthetase 3
  TNFAIP3 interacting protein 2
  tubulin, gamma 1
  ubiquitin like modifier activating enzyme 5
  ubiquitin specific peptidase 48
  zinc finger CCHC-type containing 8

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.