Hnrnpk, heterogeneous nuclear ribonucleoprotein K

Hnrnpk, heterogeneous nuclear ribonucleoprotein K

• The protein encoded by this gene is a component of the heterogeneous nuclear ribonucleoprotein (hnRNP) complex, and is a poly-cytosine binding protein (PCBP). It is found in multiple subcellular compartments including the nucleus, cytoplasm and mitochondria. This gene product is thought to interact with RNA, DNA, and protein, and is involved in multiple cellular processes, including transcription, chromatin remodeling, DNA damage response, signal transduction, mRNA splicing, export, and translation. Multiple transcript variants and protein isoforms exist, with some isoforms containing a unique C-terminus. There are four pseudogenes of this gene, found on chromosomes 2, 3, 7 and 13. [provided by RefSeq, Aug 2014]

• (No alternate names found)
• NCBI Gene ID: 15387
• Species: Mus musculus (Mouse)
• UNIPROT ID#>>Q3U9Q3
  UNIPROT ID#>>Q5FWJ5
  UNIPROT ID#>>B2M1R6
  UNIPROT ID#>>P61979
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

heterogeneous nuclear ribonucleoprotein K interacts with:

• 3-phosphoglycerate dehydrogenase
  5'-3' exoribonuclease 2
  A kinase (PRKA) anchor protein 8
  Aly/REF export factor
  BAF nuclear assembly factor 1
  BCL2-associated transcription factor 1
  BRX1, biogenesis of ribosomes
  bystin-like
  cell division cycle 5-like (S. pombe)
  centromere protein V
  cullin 3
  CWC27 spliceosome-associated protein
  DAZ associated protein 1
  DEAD box helicase 1
  DEAD box helicase 17
  DEAD box helicase 18
  DEAD box helicase 27
  DEAD box helicase 39a
  DEAD box helicase 39b
  DExD box helicase 21
  dyskeratosis congenita 1, dyskerin
  EBNA1 binding protein 2
  ELAV (embryonic lethal, abnormal vision)-like 1 (Hu antigen R)
  elongation factor Tu GTP binding domain containing 2
  eukaryotic translation initiation factor 4A3
  eukaryotic translation initiation factor 6
  family with sequence similarity 120, member A
  Fanconi anemia, complementation group D2
  F-box protein 32
  fermitin family member 2
  FtsJ RNA methyltransferase homolog 3 (E. coli)
  fused in sarcoma
  GAR1 ribonucleoprotein
  GTP binding protein 4
  guanine nucleotide binding protein-like 3 (nucleolar)
  heat shock protein 1 (chaperonin)
  heterochromatin protein 1, binding protein 3
  heterogeneous nuclear ribonucleoprotein A0
  heterogeneous nuclear ribonucleoprotein A2/B1
  heterogeneous nuclear ribonucleoprotein A3
  heterogeneous nuclear ribonucleoprotein F
  heterogeneous nuclear ribonucleoprotein H1
  heterogeneous nuclear ribonucleoprotein H2
  heterogeneous nuclear ribonucleoprotein K
  heterogeneous nuclear ribonucleoprotein L
  heterogeneous nuclear ribonucleoprotein M
  heterogeneous nuclear ribonucleoprotein U
  heterogeneous nuclear ribonucleoprotein U-like 2
  hnRNP-associated with lethal yellow
  insulin-like growth factor 2 mRNA binding protein 1
  integrin alpha 2b
  interleukin enhancer binding factor 2
  interleukin enhancer binding factor 3
  KH domain containing, RNA binding, signal transduction associated 1
  KH-type splicing regulatory protein
  La ribonucleoprotein domain family, member 7
  lectin, galactose binding, soluble 1
  LSM3 homolog, U6 small nuclear RNA and mRNA degradation associated
  Ly1 antibody reactive clone
  mago homolog, exon junction complex core component
  matrin 3
  microtubule-associated protein tau
  minichromosome maintenance complex component 3
  Mov10 RISC complex RNA helicase
  mRNA turnover 4, ribosome maturation factor
  Mtr4 exosome RNA helicase
  myelin basic protein expression factor 2, repressor
  myelocytomatosis oncogene
  NOL1/NOP2/Sun domain family member 2
  non-catalytic region of tyrosine kinase adaptor protein 2
  non-POU-domain-containing, octamer binding protein
  NOP16 nucleolar protein
  NOP58 ribonucleoprotein
  nuclear factor I/X
  nucleolar protein interacting with the FHA domain of MKI67
  optic atrophy 3
  orthodenticle homeobox 2
  peptidylprolyl isomerase (cyclophilin)-like 1
  peptidylprolyl isomerase domain and WD repeat containing 1
  peroxiredoxin 1
  pescadillo ribosomal biogenesis factor 1
  pleiotropic regulator 1
  poly(A) binding protein, cytoplasmic 1
  poly(rC) binding protein 1
  poly(rC) binding protein 2
  polypyrimidine tract binding protein 3
  potassium large conductance calcium-activated channel, subfamily M, alpha member 1
  pre-mRNA processing factor 19
  pre-mRNA processing factor 8
  programmed cell death 11
  protein arginine N-methyltransferase 1
  protein phosphatase 1 catalytic subunit alpha
  protein phosphatase 1 catalytic subunit gamma
  protein phosphatase 1 catalytic subunit gamma B
  protein phosphatase 1, regulatory subunit 9B
  pumilio RNA-binding family member 3
  Rac family small GTPase 1
  Rac family small GTPase 3
  replication protein A1
  ribonuclease/angiogenin inhibitor 1
  ribosomal L1 domain containing 1
  ribosomal protein L10
  ribosomal protein L10-like
  ribosomal protein L11
  ribosomal protein L13A
  ribosomal protein L14
  ribosomal protein L15
  ribosomal protein L18
  ribosomal protein L18A
  ribosomal protein L19
  ribosomal protein L22
  ribosomal protein L24
  ribosomal protein L28
  ribosomal protein L29
  ribosomal protein L3
  ribosomal protein L31
  ribosomal protein L32
  ribosomal protein L34
  ribosomal protein L34, pseudogene 1
  ribosomal protein L35A
  ribosomal protein L4
  ribosomal protein L6
  ribosomal protein L7
  ribosomal protein L7-like 1
  ribosomal protein L8
  ribosomal protein S19 binding protein 1
  ribosomal protein S24
  ribosomal protein S26
  ribosomal protein S27
  ribosomal protein S6
  ribosomal protein S7
  ribosomal protein S8
  ribosomal protein S9
  ribosomal protein, large, P1
  ribosomal RNA processing 1 homolog (S. cerevisiae)
  ribosomal RNA processing 12 homolog (S. cerevisiae)
  ribosome binding protein 1
  ribosome biogenesis regulator 1
  ribosome production factor 2 homolog
  RNA 2',3'-cyclic phosphate and 5'-OH ligase
  RNA binding motif (RNP1, RRM) protein 3
  RNA binding motif protein 14
  RNA binding motif protein 8a
  RNA binding protein gene with multiple splicing
  RNA pseudouridylate synthase domain containing 4
  RNA transcription, translation and transport factor
  RRP9, small subunit (SSU) processome component, homolog (yeast)
  scaffold attachment factor B
  serine and arginine-rich splicing factor 1
  serine and arginine-rich splicing factor 2
  serine and arginine-rich splicing factor 3
  serine and arginine-rich splicing factor 5
  serine and arginine-rich splicing factor 6
  serine and arginine-rich splicing factor 7
  serine/arginine repetitive matrix 1
  serine/arginine repetitive matrix 2
  serrate RNA effector molecule homolog (Arabidopsis)
  Sjogren syndrome antigen B
  small nuclear ribonucleoprotein 200 (U5)
  small nuclear ribonucleoprotein B
  small nuclear ribonucleoprotein D1
  small nuclear ribonucleoprotein D2
  small nuclear ribonucleoprotein D3
  small nuclear ribonucleoprotein N
  small nuclear ribonucleoprotein polypeptide G
  SNU13 homolog, small nuclear ribonucleoprotein (U4/U6.U5)
  SNW domain containing 1
  splicing factor 3a, subunit 3
  splicing factor 3b, subunit 1
  splicing factor 3b, subunit 3
  splicing factor proline/glutamine rich (polypyrimidine tract binding protein associated)
  synaptotagmin binding, cytoplasmic RNA interacting protein
  TAR DNA binding protein
  thioredoxin-like 1
  thrombospondin, type I, domain containing 7A
  tight junction protein 1
  topoisomerase (DNA) I
  transcription factor E3
  transformer 2 beta
  tripartite motif-containing 28
  tubulin, alpha 1A
  tubulin, alpha 1B
  tubulin, alpha 1C
  tubulin, beta 4B class IVB
  tubulin, beta 5 class I
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide
  U2 small nuclear ribonucleoprotein auxiliary factor (U2AF) 2
  UDP-glucose dehydrogenase
  UTP18 small subunit processome component
  UTP6 small subunit processome component
  voltage-dependent anion channel 2
  WD repeat domain 12
  WD repeat domain 43
  Y box protein 1
  Y box protein 3
  zinc finger protein 326

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.