RAET1E, retinoic acid early transcript 1E

RAET1E, retinoic acid early transcript 1E

• This gene belong to the RAET1 family, which consists of major histocompatibility complex (MHC) class I-related genes located in a cluster on chromosome 6q24.2-q25.3. This and RAET1G protein differ from other RAET1 proteins in that they have type I membrane-spanning sequences at their C termini rather than glycosylphosphatidylinositol anchor sequences. This protein functions as a ligand for NKG2D receptor, which is expressed on the surface of several types of immune cells, and is involved in innate and adaptive immune responses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Aug 2011]

• Gene Synonyms (LETAL, N2DL-4, NKG2DL4, RAET1E2, RL-4, ULBP4, bA350J20.7, retinoic acid early transcript 1E, NKG2D ligand 4, RAE-1-like transcript 4, UL16-binding protein 4, lymphocyte effector toxicity activation ligand,)
• NCBI Gene ID: 135250
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8TD07
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

retinoic acid early transcript 1E interacts with:

• ALG11 alpha-1,2-mannosyltransferase
  natural killer cell cytotoxicity receptor 3 ligand 1
  retinoic acid early transcript 1E

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.