MITD1, microtubule interacting and trafficking domain containing 1

MITD1, microtubule interacting and trafficking domain containing 1

• Abscission, the separation of daughter cells at the end of cytokinesis, is effected by endosomal sorting complexes required for transport III (ESCRT-III). The protein encoded by this gene functions as a homodimer, with the N-termini binding to a subset of ESCRT-III subunits and the C-termini binding to membranes. The encoded protein regulates ESCRT-III activity and is required for proper cytokinesis. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

• Gene Synonyms (MIT domain-containing protein 1, MIT, microtubule interacting and transport, domain containing 1,)
• NCBI Gene ID: 129531
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8WV92
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

microtubule interacting and trafficking domain containing 1 interacts with:

• microtubule interacting and trafficking domain containing 1
  SID1 transmembrane family, member 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.