HEXIM2, HEXIM P-TEFb complex subunit 2

HEXIM2, HEXIM P-TEFb complex subunit 2

• This gene encodes a member of the HEXIM family of proteins. This protein is a component of the 7SK small nuclear ribonucleoprotein. This protein has been found to negatively regulate the kinase activity of the cyclin-dependent kinase P-TEFb, which phosphorylates multiple target proteins to promote transcriptional elongation. This gene is located approximately 7 kb downstream from related family member HEXIM1 on chromosome 17. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2015]

• Gene Synonyms (L3, protein HEXIM2, MAQ1 paralog, hexamethylene bis-acetamide inducible 2, hexamethylene bis-acetamide-inducible protein 2, hexamethylene bisacetamide inducible 2, hexamethylene-bis-acetamide-inducible transcript 2,)
• NCBI Gene ID: 124790
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q96MH2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

HEXIM P-TEFb complex subunit 2 interacts with:

• Fer3 like bHLH transcription factor
  HEXIM P-TEFb complex subunit 2
  interactor of HORMAD1 1
  keratin associated protein 13-3
  keratinocyte proline rich protein
  sprouty related EVH1 domain containing 1
  stabilizer of axonemal microtubules 1
  zinc finger protein 558
  zinc finger protein 699
  zinc finger protein 789

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.