PLPBP, pyridoxal phosphate binding protein

PLPBP, pyridoxal phosphate binding protein

• This gene encodes a pyridoxal 5'-phosphate binding protein involved in the homeostatic regulation of intracellular pyridoxal 5'-phosphate. This gene has a tumor suppressive effect on hepatocellular carcinoma and other solid tumors of epithelial origin. Naturally occurring mutations in this gene are associated with a pyridoxine-dependent epilepsy. [provided by RefSeq, Mar 2017]

• Gene Synonyms (pyridoxal phosphate homeostasis protein, PLP homeostasis protein, proline synthase co-transcribed bacterial homolog protein, proline synthetase co-transcribed bacterial homolog protein, EPVB6D, PROSC,)
• NCBI Gene ID: 11212
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O94903
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

pyridoxal phosphate binding protein interacts with:

• 2-oxoglutarate and iron dependent oxygenase domain containing 1
  AAR2 splicing factor
  acireductone dioxygenase 1
  ADP ribosylation factor interacting protein 1
  anaphase promoting complex subunit 15
  ankyrin repeat and SOCS box containing 6
  cell division cycle associated 5
  chromobox 4
  cysteine and histidine rich domain containing 1
  heterogeneous nuclear ribonucleoprotein A3
  isochorismatase domain containing 1
  kinesin light chain 2
  MCTS1 re-initiation and release factor
  myelin expression factor 2
  N-acetylglucosamine kinase
  oxidoreductase NAD binding domain containing 1
  par-6 family cell polarity regulator beta
  phosphoglycerate dehydrogenase
  phosphohistidine phosphatase 1
  PIH1 domain containing 1
  pleckstrin homology domain containing A4
  SBDS ribosome maturation factor
  serine and arginine-rich splicing factor 1
  serine/threonine kinase 26
  sestrin 2
  shugoshin 2A
  solute carrier family 25 member 32
  TatD DNase domain containing 1
  trimethylguanosine synthase 1
  twinfilin actin binding protein 2
  UBX domain protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.