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WDR45, WD repeat domain 45

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WDR45, WD repeat domain 45

  • This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This gene has a pseudogene at chromosome 4q31.3. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene, but the biological validity and full-length nature of some variants have not been determined. [provided by RefSeq, Jul 2008]

  • Gene Synonyms (WD repeat domain phosphoinositide-interacting protein 4, WD repeat domain, X-linked 1, WD repeat-containing protein 45, WD45 repeat protein interacting with phosphoinositides 4, neurodegeneration with brain iron accumulation 4, neurodegeneration with brain iron accumulation 5, JM5, NBIA4, NBIA5, WDRX1, WIPI-4, WIPI4,)
  • NCBI Gene ID: 11152
  • Species: Homo sapiens (Human)
  • UNIPROT ID#>>Q9Y484
    UNIPROT ID#>>A0A024QYX1
  • View the NCBI Database for this Gene »

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

WD repeat domain 45 interacts with:

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.

The information on this page was collected from publicly accessible databases, and is periodically updated. Promega makes no claims to accuracy, or ownership of these genes.

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