NPC2, NPC intracellular cholesterol transporter 2

NPC2, NPC intracellular cholesterol transporter 2

• This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy. [provided by RefSeq, Jul 2008]

• Gene Synonyms (EDDM1, HE1, NPC intracellular cholesterol transporter 2, Niemann-Pick disease type C2 protein, epididymal protein 1, epididymis secretory sperm binding protein, human epididymis-specific protein 1, tissue-specific secretory protein,)
• NCBI Gene ID: 10577
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P61916
  UNIPROT ID#>>A0A024R6C0
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

NPC intracellular cholesterol transporter 2 interacts with:

• dehydrodolichyl diphosphate synthase subunit
  ERBB receptor feedback inhibitor 1
  immunity related GTPase Q
  LIM domain binding 3
  NEDD4 like E3 ubiquitin protein ligase
  nudix hydrolase 19
  PAX interacting protein 1
  Ras related GTP binding A
  transmembrane serine protease 11B

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.