AGPAT1, 1-acylglycerol-3-phosphate O-acyltransferase 1

AGPAT1, 1-acylglycerol-3-phosphate O-acyltransferase 1

• This gene encodes an enzyme that converts lysophosphatidic acid (LPA) into phosphatidic acid (PA). LPA and PA are two phospholipids involved in signal transduction and in lipid biosynthesis in cells. This enzyme localizes to the endoplasmic reticulum. This gene is located in the class III region of the human major histocompatibility complex. Alternative splicing results in two transcript variants encoding the same protein. [provided by RefSeq, Jul 2008]

• Gene Synonyms (1-AGPAT1, G15, LPAAT-alpha, LPAATA, 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha, 1-AGP acyltransferase 1, 1-AGPAT 1, 1-acylglycerol-3-phosphate O-acyltransferase 1 (acetoacetly Coenzyme A thiolase), 1-acylglycerol-3-phosphate O-acyltransferase 1 (lysophosphatidic acid acyltransferase, alpha), epididymis secretory sperm binding protein, lysophosphatidic acid acyltransferase alpha, lysophospholipid acyltransferase,)
• NCBI Gene ID: 10554
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A024RCV5
  UNIPROT ID#>>Q99943
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

1-acylglycerol-3-phosphate O-acyltransferase 1 interacts with:

• complement component 5a receptor 2
  hepatitis A virus cellular receptor 2
  homeobox A1
  obscurin like cytoskeletal adaptor 1
  OTU deubiquitinase with linear linkage specificity like
  tectonic family member 2
  transmembrane protein 216
  UPF2 regulator of nonsense mediated mRNA decay
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.