PROCR, protein C receptor

PROCR, protein C receptor

• The protein encoded by this gene is a receptor for activated protein C, a serine protease activated by and involved in the blood coagulation pathway. The encoded protein is an N-glycosylated type I membrane protein that enhances the activation of protein C. Mutations in this gene have been associated with venous thromboembolism and myocardial infarction, as well as with late fetal loss during pregnancy. The encoded protein may also play a role in malarial infection and has been associated with cancer. [provided by RefSeq, Jul 2013]

• Gene Synonyms (CCCA, CCD41, EPCR, endothelial protein C receptor, APC receptor, CD201 antigen, activated protein C receptor, cell cycle, centrosome-associated protein, centrocyclin, protein C receptor, endothelial,)
• NCBI Gene ID: 10544
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q9UNN8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

protein C receptor interacts with:

• ATP binding cassette subfamily B member 8
  ATPase H+ transporting V1 subunit H
  cyclin L2
  F-box and leucine rich repeat protein 4
  forty-two-three domain containing 1
  gap junction protein beta 7
  glycerophosphodiester phosphodiesterase 1
  interleukin 31 receptor A
  olfactory receptor family 51 subfamily E member 2
  peroxiredoxin like 2B
  PHD finger protein 19
  transmembrane protein 185A
  vitamin K epoxide reductase complex subunit 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.