IL31RA, interleukin 31 receptor A

IL31RA, interleukin 31 receptor A

• The protein encoded by this gene belongs to the type I cytokine receptor family. This receptor, with homology to gp130, is expressed on monocytes, and is involved in IL-31 signaling via activation of STAT-3 and STAT-5. It functions either as a monomer, or as part of a receptor complex with oncostatin M receptor (OSMR). Several alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Jun 2011]

• Gene Synonyms (CRL, CRL3, GLM-R, GLMR, GPL, IL-31RA, PLCA2, PRO21384, hGLM-R, interleukin-31 receptor subunit alpha, IL-31 receptor subunit alpha, IL-31R subunit alpha, class I cytokine receptor, cytokine receptor-like 3, gp130-like monocyte receptor, soluble type I cytokine receptor CRL3, zcytoR17,)
• NCBI Gene ID: 133396
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q8NI17
  UNIPROT ID#>>B4DNJ2
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

interleukin 31 receptor A interacts with:

• calcium homeostasis modulator family member 4
  desmoglein 4
  hephaestin like 1
  lysozyme g2
  V-set and immunoglobulin domain containing 8

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.