BCKDK, branched chain keto acid dehydrogenase kinase

BCKDK, branched chain keto acid dehydrogenase kinase

• The branched-chain alpha-ketoacid dehydrogenase complex (BCKD) is an important regulator of the valine, leucine, and isoleucine catabolic pathways. The protein encoded by this gene is found in the mitochondrion, where it phosphorylates and inactivates BCKD. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2012]

• Gene Synonyms (BCKDKD, BDK, [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial, 3-methyl-2-oxobutanoate dehydrogenase [lipoamide] kinase, mitochondrial, BCKD-kinase, BCKDHKIN, branched chain alpha-ketoacid dehydrogenase kinase, branched chain ketoacid dehydrogenase kinase,)
• NCBI Gene ID: 10295
• Species: Homo sapiens (Human)
• UNIPROT ID#>>O14874
  UNIPROT ID#>>A0A024QZA9
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

branched chain keto acid dehydrogenase kinase interacts with:

• autophagy related 16 like 1
  calcium binding protein 39
  calcium binding protein 39 like
  family with sequence similarity 98 member B
  F-box protein 7
  LSM8 homolog, U6 small nuclear RNA associated
  methyltransferase like 21C
  ORC ubiquitin ligase 1
  protein phosphatase, Mg2+/Mn2+ dependent 1K
  tensin 2
  WD and tetratricopeptide repeats 1
  Z-DNA binding protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.