PATJ, PATJ crumbs cell polarity complex component

PATJ, PATJ crumbs cell polarity complex component

• This gene encodes a protein with multiple PDZ domains. PDZ domains mediate protein-protein interactions, and proteins with multiple PDZ domains often organize multimeric complexes at the plasma membrane. This protein localizes to tight junctions and to the apical membrane of epithelial cells. A similar protein in Drosophila is a scaffolding protein which tethers several members of a multimeric signaling complex in photoreceptors. [provided by RefSeq, Jul 2008]

• Gene Synonyms (inaD-like protein, PALS1-associated tight junction protein, PDZ domain protein, channel-interacting PDZ domain protein, channel-interacting PDZ domain-containing protein, inactivation no after-potential D-like protein, inactivation-no-afterpotential D-like, protein associated to tight junctions, Cipp, INADL, InaD-like, hINADL,)
• NCBI Gene ID: 10207
• Species: Homo sapiens (Human)
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

PATJ crumbs cell polarity complex component interacts with:

• anaphase promoting complex subunit 15
  angiomotin
  angiomotin like 2
  calcium voltage-gated channel auxiliary subunit gamma 2
  centrosomal protein 57 like 1
  connector enhancer of kinase suppressor of Ras 2
  crumbs cell polarity complex component 3
  cyclin dependent kinase 2 interacting protein
  ETAA1 activator of ATR kinase
  GIPC PDZ domain containing family member 2
  glutaminase 2
  histone deacetylase 7
  kinesin family member 13B
  kinesin family member 1B
  large tumor suppressor kinase 2
  lin-7 homolog C (C. elegans)
  lin-7 homolog C, crumbs cell polarity complex component
  membrane palmitoylated protein 5
  neural precursor cell expressed, developmentally down-regulated gene 1
  neuroligin 2
  N-terminal EF-hand calcium binding protein 2
  par-3 family cell polarity regulator
  PR/SET domain 16
  proteasome 26S subunit, non-ATPase 14
  protocadherin alpha subfamily C, 2
  RAB32, member RAS oncogene family
  Rho GTPase activating protein 17
  ribonuclease H2 subunit A
  ring finger protein 146
  ring finger protein 166
  salvador family WW domain containing protein 1
  tight junction protein 3
  TNFAIP3 interacting protein 2
  TP53 regulating kinase
  TPX2, microtubule-associated
  transmembrane p24 trafficking protein 2
  UFM1 specific ligase 1
  vir like m6A methyltransferase associated
  WW and C2 domain containing 1
  WW domain containing E3 ubiquitin protein ligase 2
  WW domain containing transcription regulator 1
  Yes1 associated transcriptional regulator
  yes-associated protein 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.