PQBP1, polyglutamine binding protein 1

PQBP1, polyglutamine binding protein 1

• This gene encodes a nuclear polyglutamine-binding protein that is involved with transcription activation. The encoded protein contains a WW domain. Mutations in this gene have been found in patients with Renpenning syndrome 1 and other syndromes with X-linked cognitive disability. Multiple alternatively spliced transcript variants that encode different protein isoforms have been described for this gene.[provided by RefSeq, Nov 2009]

• Gene Synonyms (polyglutamine-binding protein 1, 38 kDa nuclear protein containing a WW domain, polyglutamine tract-binding protein 1, MRX2, MRX55, MRXS3, MRXS8, NPW38, RENS1, SHS,)
• NCBI Gene ID: 10084
• Species: Homo sapiens (Human)
• UNIPROT ID#>>A0A0S2Z4V5
  UNIPROT ID#>>O60828
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

polyglutamine binding protein 1 interacts with:

• BCL6 corepressor
  COP9 signalosome subunit 7A
  ergosterol biosynthesis 28 homolog
  leucine zipper tumor suppressor 2
  ligand dependent nuclear receptor interacting factor 1
  ligand of numb-protein X 1
  mediator complex subunit 31
  microtubule associated protein RP/EB family member 1
  mitochondrial ribosomal protein L53
  mitochondrial ribosomal protein S28
  obscurin like cytoskeletal adaptor 1
  polycomb group ring finger 1
  pre-mRNA processing factor 8
  reactive intermediate imine deaminase A homolog
  ribosomal protein S6 kinase A6
  SRA stem-loop interacting RNA binding protein
  SRP receptor subunit beta
  SURP and G-patch domain containing 1
  T cell leukemia homeobox 3
  thioredoxin like 4A
  transforming growth factor, beta receptor I
  WD repeat domain 77
  WW domain binding protein 11
  WW domain binding protein 11

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.