BAG1, BAG cochaperone 1

BAG1, BAG cochaperone 1

• The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]

• Gene Synonyms (BAG family molecular chaperone regulator 1, BCL2 associated athanogene 1, BCL2-associated athanogene, Bcl-2 associating athanogene-1 protein, Bcl-2-binding protein, glucocortoid receptor-associated protein RAP46, receptor-associated protein, 46-KD, BAG-1, HAP, RAP46,)
• NCBI Gene ID: 573
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99933
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

BAG cochaperone 1 interacts with:

• acidic nuclear phosphoprotein 32 family member A
  acidic nuclear phosphoprotein 32 family member B
  actin related protein 2
  actin related protein 2/3 complex subunit 4
  adhesion regulating molecule 1
  BAG cochaperone 3
  basic helix-loop-helix family member a15
  BCL2 apoptosis regulator
  BCL2 like 1
  bromodomain containing 2
  carboxypeptidase Z
  Cbl proto-oncogene
  CD44 molecule (Indian blood group)
  centrosomal protein 72
  CF transmembrane conductance regulator
  coiled-coil domain containing 117
  coiled-coil-helix-coiled-coil-helix domain containing 10
  complement component 1, q subcomponent binding protein
  C-type lectin domain family 3 member A
  cytochrome P450 family 2 subfamily W member 1
  DnaJ heat shock protein family (Hsp40) member B1
  DnaJ heat shock protein family (Hsp40) member B4
  DnaJ heat shock protein family (Hsp40) member B6
  Ecm29 proteasome adaptor and scaffold
  elongation factor like GTPase 1
  estrogen receptor 1
  exportin 5
  far upstream element binding protein 1
  forkhead box D4
  G protein-coupled receptor class C group 5 member C
  general transcription factor IIIC subunit 2
  glucosamine-phosphate N-acetyltransferase 1
  glycogen phosphorylase L
  GrpE like 1, mitochondrial
  heat shock protein family A (Hsp70) member 1A
  heat shock protein family A (Hsp70) member 1B
  heat shock protein family A (Hsp70) member 4
  heat shock protein family A (Hsp70) member 8
  heparin binding EGF like growth factor
  kelch like family member 34
  kinesin family member C1
  leucine rich repeat kinase 1
  leucine rich repeat kinase 2
  listerin E3 ubiquitin protein ligase 1
  MET proto-oncogene, receptor tyrosine kinase
  methyltransferase like 3
  microtubule associated protein tau
  myeloid leukemia factor 2
  NGG1 interacting factor 3 like 1
  nuclear receptor subfamily 3 group C member 1
  nuclear RNA export factor 1
  O-sialoglycoprotein endopeptidase
  pantothenate kinase 4 (inactive)
  Parkinsonism associated deglycase
  paternally expressed 10
  peptidylprolyl isomerase like 3
  platelet derived growth factor receptor beta
  potassium inwardly rectifying channel subfamily J member 10
  potassium voltage-gated channel subfamily D member 2
  POTE ankyrin domain family member C
  PR/SET domain 5
  proteasome 20S subunit alpha 3
  proteasome 26S subunit, ATPase 1
  proteasome 26S subunit, non-ATPase 1
  proteasome 26S subunit, non-ATPase 2
  proteasome 26S subunit, non-ATPase 5
  protein phosphatase 1 regulatory subunit 15A
  Raf-1 proto-oncogene, serine/threonine kinase
  Ran GTPase activating protein 1
  RB transcriptional corepressor 1
  regulation of nuclear pre-mRNA domain containing 1B
  replication protein A3
  retinoic acid receptor alpha
  RIO kinase 1
  salvador family WW domain containing protein 1
  Scm polycomb group protein like 2
  SEM1 26S proteasome complex subunit
  SET nuclear oncogene
  SH3 domain containing GRB2 like 1, endophilin A2
  siah E3 ubiquitin protein ligase 1
  STIP1 homology and U-box containing protein 1
  synoviolin 1
  target of myb1 like 1 membrane trafficking protein
  thioredoxin domain containing 9
  THUMP domain containing 1
  tripartite motif containing 27
  tumor protein p53
  vitamin D receptor
  YY1 associated protein 1
  ZPR1 zinc finger

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.