ATP5MC3, ATP synthase membrane subunit c locus 3

ATP5MC3, ATP synthase membrane subunit c locus 3

• This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, Fo, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and a single representative of the other 3. The proton channel seems to have nine subunits (a, b, c, d, e, f, g, F6 and 8). This gene is one of three genes that encode subunit c of the proton channel. Each of the three genes have distinct mitochondrial import sequences but encode the identical mature protein. Alternatively spliced transcript variants encoding different proteins have been identified. [provided by RefSeq, Jun 2010]

• Gene Synonyms (ATP synthase F(0) complex subunit C3, mitochondrial, ATP synthase lipid-binding protein, mitochondrial, ATP synthase proteolipid P3, ATP synthase proton-transporting mitochondrial F(0) complex subunit C3, ATP synthase subunit 9, ATP synthase, H+ transporting, mitochondrial F0 complex, subunit C3 (subunit 9), ATP synthase, H+ transporting, mitochondrial Fo complex subunit C3 (subunit 9), ATP synthase, mitochondrial, C subunit-3, ATPase protein 9, ATPase subunit C, ATP5G3, P3,)
• NCBI Gene ID: 518
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P48201
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

ATP synthase membrane subunit c locus 3 interacts with:

• abhydrolase domain containing 16A, phospholipase
  ATP synthase membrane subunit c locus 3
  collagen type XX alpha 1 chain
  estrogen receptor 2
  GH3 domain containing
  glucagon like peptide 1 receptor
  golgin A4
  melatonin receptor 1A
  Mov10 RISC complex RNA helicase
  nuclear RNA export factor 1
  transmembrane protein 31
  vitamin K epoxide reductase complex subunit 1

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.