ASCL2, achaete-scute family bHLH transcription factor 2

ASCL2, achaete-scute family bHLH transcription factor 2

• This gene is a member of the basic helix-loop-helix (BHLH) family of transcription factors. It activates transcription by binding to the E box (5'-CANNTG-3'). Dimerization with other BHLH proteins is required for efficient DNA binding. Involved in the determination of the neuronal precursors in the peripheral nervous system and the central nervous system. [provided by RefSeq, Jul 2008]

• Gene Synonyms (achaete-scute homolog 2, achaete-scute complex homolog 2, achaete-scute complex-like 2, class A basic helix-loop-helix protein 45, mammalian achaete/scute homologue 2, ASH2, HASH2, MASH2, bHLHa45,)
• NCBI Gene ID: 430
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q99929
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

achaete-scute family bHLH transcription factor 2 interacts with:

• calmodulin 1
  calmodulin 3
  E1A binding protein p300
  host cell factor C1
  lysine methyltransferase 2C
  nuclear receptor coactivator 6
  RB binding protein 5, histone lysine methyltransferase complex subunit
  RecQ like helicase 4
  tubulin alpha 1a

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.