ARR3, arrestin 3

ARR3, arrestin 3

• The protein encoded by this gene is a non-visual arrestin which binds to agonist-activated, phosphorylated G protein-coupled receptors. This binding uncouples the receptor from the heterotrimeric G protein, resulting in termination of the G protein-coupled receptor signaling. The encoded protein also is a part of the centrosome, interacting with gamma-tubulin to help regulate proper centrosome function. [provided by RefSeq, May 2016]

• Gene Synonyms (arrestin-C, C-arrestin, arrestin 3 retinal (X-arrestin), arrestin 4, retinal cone arrestin-3, ARRX, MYP26, cArr,)
• NCBI Gene ID: 407
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P36575
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

arrestin 3 interacts with:

• adaptor related protein complex 3 subunit beta 1
  arrestin 3
  arrestin beta 1
  arrestin beta 2
  calpain small subunit 1
  casein kinase 2 alpha 1
  clathrin heavy chain
  dishevelled segment polarity protein 2
  follicle stimulating hormone receptor
  glycine N-methyltransferase
  membrane associated ring-CH-type finger 8
  mitogen-activated protein kinase kinase 7
  opsin 1, medium wave sensitive 2
  opsin 4
  platelet activating factor receptor
  polo like kinase 4
  REST corepressor 2
  rhodopsin
  ribonuclease A family member k6
  SRC proto-oncogene, non-receptor tyrosine kinase
  zinc finger and BTB domain containing 43
  zinc finger protein 496

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.