AQP6, aquaporin 6

AQP6, aquaporin 6

• The protein encoded by this gene is an aquaporin protein, which functions as a water channel in cells. Aquaporins are a family of small integral membrane proteins related to the major intrinsic protein (MIP or AQP0). This protein is specific for the kidney. This gene and related family members AQP0, AQP2, and AQP5 reside in a cluster on chromosome 12q13. [provided by RefSeq, Jul 2008]

• Gene Synonyms (aquaporin-6, AQP-6, aquaporin 2-like, kidney specific, aquaporin-6, kidney specific, hKID, kidney-specific aquaporin, AQP2L, KID,)
• NCBI Gene ID: 363
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q13520
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

aquaporin 6 interacts with:

• 1-acylglycerol-3-phosphate O-acyltransferase 3
  1-acylglycerol-3-phosphate O-acyltransferase 4
  abhydrolase domain containing 16A, phospholipase
  acyl-CoA synthetase long chain family member 5
  adhesion G protein-coupled receptor E2
  adiponectin, C1Q and collagen domain containing
  ADP ribosylation factor like GTPase 6 interacting protein 1
  ADP ribosylation factor like GTPase 6 interacting protein 6
  alkylglycerol monooxygenase
  androgen induced 1
  angiotensin II receptor associated protein
  ankyrin repeat domain 46
  ARV1 homolog, fatty acid homeostasis modulator
  ATP binding cassette subfamily G member 1
  ATPase 13A1
  ATPase H+ transporting V0 subunit c
  basigin (Ok blood group)
  Bet1 golgi vesicular membrane trafficking protein
  bone morphogenetic protein 10
  BRICHOS domain containing 5
  butyrophilin subfamily 2 member A2
  C2CD2 like
  cathepsin A
  C-C motif chemokine ligand 22
  C-C motif chemokine ligand 4 like 2
  CD52 molecule
  CD68 molecule
  CD81 molecule
  CDP-diacylglycerol--inositol 3-phosphatidyltransferase
  cell growth regulator with EF-hand domain 1
  chromosome 14 open reading frame 180
  chromosome 3 open reading frame 52
  chromosome 4 open reading frame 3
  chromosome 5 open reading frame 46
  chromosome X open reading frame 66
  CKLF like MARVEL transmembrane domain containing 3
  CKLF like MARVEL transmembrane domain containing 5
  CKLF like MARVEL transmembrane domain containing 7
  claudin 19
  claudin 4
  claudin domain containing 2
  coiled-coil domain containing 167
  complement C5
  corin, serine peptidase
  cornichon family AMPA receptor auxiliary protein 1
  cornichon family AMPA receptor auxiliary protein 3
  cortexin 3
  C-X-C motif chemokine ligand 16
  C-X-C motif chemokine ligand 9
  cytochrome b-245 chaperone 1
  cytochrome b5 reductase 3
  cytochrome b5 type B
  cytochrome b561
  cytochrome b561 family member A3
  cytochrome b561 family member D1
  cytochrome c oxidase assembly factor COX20
  cytochrome P450 family 4 subfamily F member 2
  cytochrome P450 family 4 subfamily F member 22
  defensin beta 103A
  defensin beta 103B
  defensin beta 108B
  defensin beta 127
  dehydrogenase/reductase X-linked
  derlin 1
  diacylglycerol O-acyltransferase 2 like 6
  DnaJ heat shock protein family (Hsp40) member C30
  EBP cholestenol delta-isomerase
  endoplasmic reticulum metallopeptidase 1
  ephrin A5
  epithelial membrane protein 1
  epithelial membrane protein 3
  ER membrane protein complex subunit 6
  ergosterol biosynthesis 28 homolog
  family with sequence similarity 177 member A1
  farnesyl-diphosphate farnesyltransferase 1
  fatty acid 2-hydroxylase
  fatty acid hydroxylase domain containing 2
  FUN14 domain containing 2
  FXYD domain containing ion transport regulator 3
  FXYD domain containing ion transport regulator 6
  FXYD6-FXYD2 readthrough
  G protein-coupled receptor 151
  G protein-coupled receptor 152
  G protein-coupled receptor 25
  gap junction protein beta 2
  gastrin
  gastrokine 1
  glutamate metabotropic receptor 2
  glycophorin C (Gerbich blood group)
  golgi SNAP receptor complex member 2
  golgi transport 1A
  GTPase, IMAP family member 1
  GTPase, IMAP family member 5
  heme oxygenase 1
  heme oxygenase 2
  HIV-1 Tat interactive protein 2
  hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
  insulin induced gene 1
  insulin induced gene 2
  insulin like growth factor binding protein 5
  integrin subunit alpha M
  interferon gamma receptor 1
  interferon induced transmembrane protein 3
  isoprenylcysteine carboxyl methyltransferase
  jagunal homolog 1
  junctophilin 1
  lanosterol synthase
  LEM domain containing 1
  leptin receptor overlapping transcript
  leucyl and cystinyl aminopeptidase
  LHFPL tetraspan subfamily member 5
  lymphocyte antigen 6 family member D
  lysophosphatidic acid receptor 3
  major facilitator superfamily domain containing 3
  major facilitator superfamily domain containing 5
  mal, T cell differentiation protein
  mal, T cell differentiation protein 2
  mal, T cell differentiation protein like
  maltase-glucoamylase
  matrix metallopeptidase 14
  membrane associated ring-CH-type finger 2
  membrane associated ring-CH-type finger 5
  membrane spanning 4-domains A1
  membrane spanning 4-domains A13
  mitochondrial fission factor
  monoglyceride lipase
  myeloid associated differentiation marker like 2
  natural killer cell granule protein 7
  neuraminidase 1
  ninjurin 1
  ninjurin 2
  nurim
  ORMDL sphingolipid biosynthesis regulator 1
  ORMDL sphingolipid biosynthesis regulator 2
  ORMDL sphingolipid biosynthesis regulator 3
  OTU deubiquitinase with linear linkage specificity like
  PDZK1 interacting protein 1
  PEDS1-UBE2V1 readthrough
  peroxisomal biogenesis factor 11 gamma
  peroxisomal biogenesis factor 16
  phosphatidylethanolamine N-methyltransferase
  phosphatidylinositol glycan anchor biosynthesis class F
  phospholipid phosphatase 6
  plasmolipin
  potassium two pore domain channel subfamily K member 1
  PRA1 domain family member 2
  progestagen associated endometrial protein
  proline rich protein BstNI subfamily 1
  proline rich protein HaeIII subfamily 1
  proline rich transmembrane protein 2
  protein tyrosine phosphatase non-receptor type 1
  protein tyrosine phosphatase non-receptor type 9
  proteolipid protein 1
  RAB18, member RAS oncogene family
  receptor transporter protein 2
  reprimo, TP53 dependent G2 arrest mediator homolog
  RFT1 homolog
  Rh blood group D antigen
  RUS family member 1
  SAC1 like phosphatidylinositide phosphatase
  SEC22 homolog A, vesicle trafficking protein
  SEC22 homolog B, vesicle trafficking protein
  SEC61 translocon subunit gamma
  secondary ossification center associated regulator of chondrocyte maturation
  secreted frizzled related protein 4
  secretoglobin family 1A member 1
  secretory carrier membrane protein 4
  secretory carrier membrane protein 5
  selenoprotein K
  SFT2 domain containing 1
  SFT2 domain containing 2
  sideroflexin 1
  sideroflexin 2
  sideroflexin 3
  sideroflexin 5
  single-pass membrane protein with coiled-coil domains 4
  small cell adhesion glycoprotein
  small EDRK-rich factor 1A
  small EDRK-rich factor 1B
  small integral membrane protein 1 (Vel blood group)
  small transmembrane regulator of ion transport 1
  solute carrier family 16 member 12
  solute carrier family 16 member 13
  solute carrier family 25 member 46
  solute carrier family 30 member 2
  solute carrier family 30 member 8
  solute carrier family 35 member A1
  solute carrier family 35 member B1
  solute carrier family 35 member B2
  solute carrier family 35 member B4
  solute carrier family 35 member E4
  solute carrier family 35 member F1
  solute carrier family 35 member F6
  solute carrier family 35 member G2
  solute carrier family 38 member 1
  solute carrier family 39 member 2
  solute carrier family 39 member 7
  solute carrier family 39 member 9
  solute carrier family 41 member 1
  solute carrier family 41 member 2
  solute carrier family 52 member 1
  solute carrier family 66 member 1
  solute carrier family 66 member 2
  solute carrier family 7 member 1
  solute carrier family 7 member 8
  solute carrier organic anion transporter family member 3A1
  ST6 beta-galactoside alpha-2,6-sialyltransferase 2
  StAR related lipid transfer domain containing 3
  statherin
  stearoyl-CoA desaturase
  stress associated endoplasmic reticulum protein 1
  stress associated endoplasmic reticulum protein family member 2
  synapse differentiation inducing 1
  synaptogyrin 1
  synaptojanin 2 binding protein
  syntaxin 12
  syntaxin 1B
  syntaxin 3
  syntaxin 5
  syntaxin 6
  syntaxin 7
  TBC1 domain family member 20
  thioredoxin related transmembrane protein 2
  three prime repair exonuclease 1
  thrombomodulin
  thrombospondin type 1 domain containing 7A
  thrombospondin type 1 domain containing 7B
  TLC domain containing 1
  TNF receptor superfamily member 10c
  transferrin receptor
  translocase of inner mitochondrial membrane 23
  translocase of outer mitochondrial membrane 22
  translocase of outer mitochondrial membrane 6
  translocator protein 2
  transmembrane and ubiquitin like domain containing 2
  transmembrane inner ear
  transmembrane protein 100
  transmembrane protein 107
  transmembrane protein 115
  transmembrane protein 119
  transmembrane protein 120A
  transmembrane protein 120B
  transmembrane protein 128
  transmembrane protein 140
  transmembrane protein 143
  transmembrane protein 144
  transmembrane protein 14A
  transmembrane protein 167B
  transmembrane protein 19
  transmembrane protein 199
  transmembrane protein 203
  transmembrane protein 218
  transmembrane protein 222
  transmembrane protein 229B
  transmembrane protein 234
  transmembrane protein 239
  transmembrane protein 242
  transmembrane protein 243
  transmembrane protein 254
  transmembrane protein 262
  transmembrane protein 42
  transmembrane protein 50A
  transmembrane protein 51
  transmembrane protein 60
  transmembrane protein 65
  transmembrane protein 69
  transmembrane protein 74
  transmembrane protein 86B
  transmembrane protein 97
  transporter 1, ATP binding cassette subfamily B member
  tumor protein p63 regulated 1
  ubiquitin conjugating enzyme E2 J2
  ubiquitin domain containing 2
  UBX domain protein 8
  unc-50 inner nuclear membrane RNA binding protein
  unc-93 homolog A
  unconventional SNARE in the ER 1
  vacuolar ATPase assembly factor VMA21
  VAMP associated protein A
  VAMP associated protein B and C
  vesicle associated membrane protein 1
  vesicle associated membrane protein 2
  vesicle associated membrane protein 3
  vesicle associated membrane protein 4
  vesicle associated membrane protein 5
  vesicle transport through interaction with t-SNAREs 1B
  vezatin, adherens junctions transmembrane protein
  vitamin K epoxide reductase complex subunit 1 like 1
  VRK serine/threonine kinase 2
  V-set and transmembrane domain containing 1
  wolframin ER transmembrane glycoprotein
  XK related 3
  Yip1 domain family member 1
  Yip1 domain family member 2
  Yip1 domain family member 4
  Yip1 domain family member 6
  Yip1 interacting factor homolog A, membrane trafficking protein
  zinc finger DHHC-type containing 24
  zinc finger DHHC-type palmitoyltransferase 21
  zinc finger protein 587

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.