ANXA1, annexin A1

ANXA1, annexin A1

• This gene encodes a membrane-localized protein that binds phospholipids. This protein inhibits phospholipase A2 and has anti-inflammatory activity. Loss of function or expression of this gene has been detected in multiple tumors. [provided by RefSeq, Dec 2014]

• Gene Synonyms (annexin A1, annexin I (lipocortin I), annexin-1, calpactin II, calpactin-2, chromobindin-9, epididymis secretory sperm binding protein, phospholipase A2 inhibitory protein, ANX1, LPC1,)
• NCBI Gene ID: 301
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5TZZ9
  UNIPROT ID#>>P04083
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

annexin A1 interacts with:

• AAR2 splicing factor
  abhydrolase domain containing 11
  activating transcription factor 2
  amyloid beta precursor protein binding family B member 1
  annexin A1
  annexin A4
  annexin A5
  anterior gradient 2, protein disulphide isomerase family member
  ATPase H+/K+ transporting subunit alpha
  autophagy related 4B cysteine peptidase
  BAG cochaperone 3
  bone morphogenetic protein receptor, type 1A
  BRCA1 DNA repair associated
  cadherin 1
  CD4 molecule
  cell division cycle 73
  centrosomal protein 128
  centrosomal protein 152
  centrosomal protein 89
  CF transmembrane conductance regulator
  chaperonin containing TCP1 subunit 7
  coiled-coil domain containing 88A
  COP9 signalosome subunit 6
  core-binding factor subunit beta
  cullin 5
  cullin 7
  CXXC motif containing zinc binding protein
  cyclic GMP-AMP synthase
  cyclin dependent kinase 2
  cysteine sulfinic acid decarboxylase
  cysteinyl-tRNA synthetase 2, mitochondrial
  DEAD-box helicase 19B
  deoxyguanosine kinase
  developmental pluripotency-associated 3
  discs large MAGUK scaffold protein 3
  dynactin subunit 1
  dysferlin
  elongation factor Tu GTP binding domain containing 2
  enolase 1
  epidermal growth factor receptor
  ergosterol biosynthesis 28 homolog
  estrogen receptor 2
  FA complementation group D2
  Fas associated factor 1
  fatty acid binding protein 3
  FERM domain containing 1
  fibronectin 1
  formyl peptide receptor 1
  frataxin
  fumarylacetoacetate hydrolase domain containing 1
  G protein subunit beta 2
  G3BP stress granule assembly factor 1
  glyceraldehyde-3-phosphate dehydrogenase
  glypican 1
  golgi transport 1B
  guanylate kinase 1
  heat shock protein family B (small) member 1
  HECT, C2 and WW domain containing E3 ubiquitin protein ligase 2
  heterogeneous nuclear ribonucleoprotein A1
  high mobility group AT-hook 1
  histidine triad nucleotide binding protein 1
  HRas proto-oncogene, GTPase
  inhibitor of nuclear factor kappa B kinase regulatory subunit gamma
  integrin subunit alpha 4
  kelch like family member 23
  keratin 8
  killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 2
  kinesin family member 11
  kinesin family member C1
  KRAS proto-oncogene, GTPase
  ligand dependent nuclear receptor interacting factor 1
  lunapark, ER junction formation factor
  lysine methyltransferase 2B
  Meis homeobox 2
  methionine sulfoxide reductase B2
  methyltransferase like 3
  microtubule associated protein 1S
  minichromosome maintenance complex component 2
  Mov10 RISC complex RNA helicase
  MYC proto-oncogene, bHLH transcription factor
  myotrophin
  NRAS proto-oncogene, GTPase
  NSL1 component of MIS12 kinetochore complex
  nuclear RNA export factor 1
  O-6-methylguanine-DNA methyltransferase
  obscurin like cytoskeletal adaptor 1
  OTU deubiquitinase, ubiquitin aldehyde binding 1
  peptidase, mitochondrial processing subunit alpha
  peptidylprolyl isomerase A
  peptidyl-tRNA hydrolase domain containing 1
  peroxiredoxin 6
  phospholipase A2 group IVA
  pre-mRNA processing factor 8
  protein kinase C iota
  protein phosphatase, Mg2+/Mn2+ dependent 1B
  Ras association domain family member 10
  receptor interacting serine/threonine kinase 1
  RELA proto-oncogene, NF-kB subunit
  replication protein A1
  RNA pseudouridine synthase D3
  S100 calcium binding protein A11
  serine/threonine kinase 4
  sirtuin 7
  SLX1 homolog B, structure-specific endonuclease subunit
  small ubiquitin like modifier 2
  SRC proto-oncogene, non-receptor tyrosine kinase
  SRY-box transcription factor 2
  superoxide dismutase 1
  thioredoxin 2
  TP53 induced glycolysis regulatory phosphatase
  trafficking from ER to golgi regulator
  transglutaminase 2
  transient receptor potential cation channel subfamily M member 7
  tripartite motif containing 25
  tumor protein p53
  tumor protein p53 binding protein 2
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  U2 small nuclear RNA auxiliary factor 2
  ubiquilin 2
  ubiquitin conjugating enzyme E2 D1
  ubiquitin conjugating enzyme E2 I
  ubiquitin C-terminal hydrolase L5
  ubiquitin protein ligase E3A
  ubiquitin specific peptidase 25
  ubiquitin specific peptidase 7
  ubiquitin specific peptidase like 1
  UDP glucuronosyltransferase family 1 member A10
  unc-119 lipid binding chaperone
  uncoupling protein 2
  vascular cell adhesion molecule 1
  WD repeat domain 77
  WT1 associated protein
  WW domain containing oxidoreductase
  X-ray repair cross complementing 6
  zinc finger and BTB domain containing 1
  zinc finger and SCAN domain containing 20

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.