DTX1, deltex E3 ubiquitin ligase 1

DTX1, deltex E3 ubiquitin ligase 1

• Studies in Drosophila have identified this gene as encoding a positive regulator of the Notch-signaling pathway. The human gene encodes a protein of unknown function; however, it may play a role in basic helix-loop-helix transcription factor activity. [provided by RefSeq, Jul 2008]

• Gene Synonyms (RNF140, hDx-1, E3 ubiquitin-protein ligase DTX1, RING-type E3 ubiquitin transferase DTX1, deltex 1, E3 ubiquitin ligase, deltex homolog 1, protein deltex-1,)
• NCBI Gene ID: 1840
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q86Y01
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

deltex E3 ubiquitin ligase 1 interacts with:

• CASP8 and FADD like apoptosis regulator
  deltex E3 ubiquitin ligase 1
  deltex E3 ubiquitin ligase 2
  deltex E3 ubiquitin ligase 3
  deltex E3 ubiquitin ligase 3L
  E1A binding protein p300
  early growth response 2
  eukaryotic translation initiation factor 3 subunit F
  G3BP stress granule assembly factor 1
  growth factor receptor bound protein 2
  itchy E3 ubiquitin protein ligase
  mitogen-activated protein kinase kinase kinase 1
  notch receptor 1
  notch receptor 2
  protein kinase cAMP-dependent type I regulatory subunit alpha
  Tax1 binding protein 3
  ubiquitin conjugating enzyme E2 C
  ubiquitin conjugating enzyme E2 D1
  ubiquitin conjugating enzyme E2 D2
  ubiquitin conjugating enzyme E2 D3
  ubiquitin conjugating enzyme E2 D4 (putative)
  ubiquitin conjugating enzyme E2 E1
  ubiquitin conjugating enzyme E2 N
  ubiquitin conjugating enzyme E2 U

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.