DLX5, distal-less homeobox 5

DLX5, distal-less homeobox 5

• This gene encodes a member of a homeobox transcription factor gene family similiar to the Drosophila distal-less gene. The encoded protein may play a role in bone development and fracture healing. Mutation in this gene, which is located in a tail-to-tail configuration with another member of the family on the long arm of chromosome 7, may be associated with split-hand/split-foot malformation. [provided by RefSeq, Jul 2008]

• Gene Synonyms (homeobox protein DLX-5, distal-less homeo box 5, split hand/foot malformation type 1 with sensorineural hearing loss, SHFM1, SHFM1D,)
• NCBI Gene ID: 1749
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P56178
  UNIPROT ID#>>Q53Y73
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

distal-less homeobox 5 interacts with:

• distal-less homeobox 5
  forkhead box A1
  forkhead box C1
  forkhead box C2
  forkhead box E1
  forkhead box I2
  forkhead box J2
  forkhead box O1
  homeobox C8
  MAGE family member D1
  msh homeobox 1
  msh homeobox 2
  nuclear receptor coactivator 2
  recombination signal binding protein for immunoglobulin kappa J region
  spen family transcriptional repressor
  SRY-box transcription factor 10
  SRY-box transcription factor 8
  TEA domain transcription factor 2

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.