ADSS2, adenylosuccinate synthase 2

ADSS2, adenylosuccinate synthase 2

• This gene encodes the enzyme adenylosuccinate synthetase which catalyzes the first committed step in the conversion of inosine monophosphate to adenosine monophosphate. A pseudogene of this gene is found on chromosome 17.[provided by RefSeq, Nov 2010]

• Gene Synonyms (ADEH, ADSS, ADSS 2, adenylosuccinate synthetase isozyme 2, AMPSase 2, IMP--aspartate ligase 2, L-type adenylosuccinate synthetase, adSS 2, adenylosuccinate synthetase (Ade(-)H-complementing), adenylosuccinate synthetase, acidic isozyme, adenylosuccinate synthetase, liver isozyme, epididymis secretory sperm binding protein,)
• NCBI Gene ID: 159
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P30520
  UNIPROT ID#>>A0A024R5Q7
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

adenylosuccinate synthase 2 interacts with:

• 3-oxoacid CoA-transferase 1
  5'-nucleotidase, cytosolic IIIA
  acidic residue methyltransferase 1
  adenylosuccinate synthase 1
  ADP ribosylation factor interacting protein 1
  aminoadipate-semialdehyde dehydrogenase-phosphopantetheinyl transferase
  amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase
  annexin A6
  anterior gradient 2, protein disulphide isomerase family member
  ATPase H+ transporting V1 subunit H
  ATPase Na+/K+ transporting subunit alpha 1
  autophagy related 10
  baculoviral IAP repeat containing 3
  cell division cycle 37, HSP90 cochaperone
  chaperonin containing TCP1 subunit 8
  charged multivesicular body protein 4A
  chromatin accessibility complex subunit 1
  chromobox 3
  C-terminal binding protein 1
  cullin 3
  deoxycytidine kinase
  destrin, actin depolymerizing factor
  DnaJ heat shock protein family (Hsp40) member A2
  eukaryotic translation elongation factor 1 alpha 1
  eukaryotic translation elongation factor 2
  eukaryotic translation initiation factor 4A3
  farnesyl diphosphate synthase
  G1 to S phase transition 2
  galectin 7
  glucosamine-phosphate N-acetyltransferase 1
  glutathione-disulfide reductase
  guanine monophosphate synthase
  H3 clustered histone 1
  heat shock protein family A (Hsp70) member 1A
  heat shock protein family A (Hsp70) member 8
  heat shock protein family B (small) member 1
  heat shock protein family D (Hsp60) member 1
  heat shock protein family E (Hsp10) member 1
  hydroxysteroid 17-beta dehydrogenase 10
  inositol monophosphatase 2
  isocitrate dehydrogenase (NADP(+)) 1
  kynureninase
  major histocompatibility complex, class I, A
  mitogen-activated protein kinase 14
  MYC proto-oncogene, bHLH transcription factor
  neuropeptide B
  NME/NM23 nucleoside diphosphate kinase 2
  NME1-NME2 readthrough
  ornithine aminotransferase
  parathymosin
  peroxiredoxin 5
  phosphofructokinase, liver type
  phosphoribosylglycinamide formyltransferase, phosphoribosylglycinamide synthetase, phosphoribosylaminoimidazole synthetase
  poly(rC) binding protein 1
  proliferating cell nuclear antigen
  protein disulfide isomerase family A member 3
  protein phosphatase 1 catalytic subunit alpha
  pterin-4 alpha-carbinolamine dehydratase 1
  RAB11A, member RAS oncogene family
  RB binding protein 7, chromatin remodeling factor
  ribonuclease/angiogenin inhibitor 1
  ribosomal protein L17
  ribosomal protein L31
  ribosomal protein S11
  ribosomal protein S15a
  ribosomal protein S16
  ribosomal protein S28
  ribosomal protein S3
  ribosomal protein S8
  ribulose-5-phosphate-3-epimerase
  SET and MYND domain containing 1
  small glutamine rich tetratricopeptide repeat containing alpha
  TAR DNA binding protein
  thimet oligopeptidase 1
  thyroid hormone receptor associated protein 3
  TRAF family member associated NFKB activator
  transaldolase 1
  transforming growth factor beta 1
  transport and golgi organization 2 homolog
  tripartite motif containing 25
  tubulin beta 3 class III
  tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein theta
  ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1
  ubiquitin conjugating enzyme E2 M
  uridine monophosphate synthetase
  valosin containing protein
  WD repeat domain 1
  Yes1 associated transcriptional regulator

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.