ANXA6, annexin A6

ANXA6, annexin A6

• Annexin VI belongs to a family of calcium-dependent membrane and phospholipid binding proteins. Several members of the annexin family have been implicated in membrane-related events along exocytotic and endocytotic pathways. The annexin VI gene is approximately 60 kbp long and contains 26 exons. It encodes a protein of about 68 kDa that consists of eight 68-amino acid repeats separated by linking sequences of variable lengths. It is highly similar to human annexins I and II sequences, each of which contain four such repeats. Annexin VI has been implicated in mediating the endosome aggregation and vesicle fusion in secreting epithelia during exocytosis. Alternatively spliced transcript variants have been described. [provided by RefSeq, Aug 2010]

• Gene Synonyms (annexin A6, 67 kDa calelectrin, annexin VI (p68), annexin-6, calcium-binding protein p68, calelectrin, calphobindin II, chromobindin-20, lipocortin VI, testis secretory sperm-binding protein Li 198a, ANX6, CBP68, CPB-II, p68, p70,)
• NCBI Gene ID: 309
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P08133
  UNIPROT ID#>>A0A0S2Z2Z6
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

annexin A6 interacts with:

• 3-oxoacid CoA-transferase 1
  aminoadipate aminotransferase
  ATPase H+ transporting V0 subunit a2
  ATPase H+/K+ transporting subunit alpha
  baculoviral IAP repeat containing 3
  CD4 molecule
  cell division cycle 73
  coiled-coil domain containing 8
  coiled-coil-helix-coiled-coil-helix domain containing 4
  complement C3d receptor 2
  cullin 5
  cyclic GMP-AMP synthase
  DNA polymerase epsilon 3, accessory subunit
  dynein light chain Tctex-type 1
  enoyl-CoA hydratase, short chain 1
  erb-b2 receptor tyrosine kinase 2
  EWS RNA binding protein 1
  G3BP stress granule assembly factor 1
  glutamic-oxaloacetic transaminase 1
  H2A.X variant histone
  heterogeneous nuclear ribonucleoprotein L
  hypoxanthine phosphoribosyltransferase 1
  interleukin 16
  isocitrate dehydrogenase (NADP(+)) 1
  kynurenine aminotransferase 3
  lamin A/C
  melatonin receptor 1B
  methylthioadenosine phosphorylase
  methyltransferase like 14
  methyltransferase like 18
  multiple coagulation factor deficiency 2, ER cargo receptor complex subunit
  mutL homolog 1
  mutS homolog 2
  neurotrophic receptor tyrosine kinase 1
  nicotinamide phosphoribosyltransferase
  NSF attachment protein alpha
  plastin 3
  protein kinase C alpha
  protein phosphatase methylesterase 1
  PTEN induced kinase 1
  ras homolog family member U
  RAS p21 protein activator 1
  S100 calcium binding protein A1
  S100 calcium binding protein B
  sirtuin 7
  SMAD specific E3 ubiquitin protein ligase 1
  synuclein alpha
  TAO kinase 3
  thimet oligopeptidase 1
  thioredoxin 2
  tight junction protein 1
  tripartite motif containing 25
  tubulin folding cofactor B
  tumor protein D52
  U2 small nuclear RNA auxiliary factor 2
  ubiquitin conjugating enzyme E2 A
  ubiquitin conjugating enzyme E2 H
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.