CSF1, colony stimulating factor 1

CSF1, colony stimulating factor 1

• The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Sep 2011]

• Gene Synonyms (macrophage colony-stimulating factor 1, colony stimulating factor 1 (macrophage), lanimostim, macrophage colony stimulating factor 1, CSF-1, MCSF,)
• NCBI Gene ID: 1435
• Species: Homo sapiens (Human)
• UNIPROT ID#>>P09603
  UNIPROT ID#>>A0A024R0A1
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

colony stimulating factor 1 interacts with:

• colony stimulating factor 1
  colony stimulating factor 1 receptor
  cysteine rich tail 1
  four and a half LIM domains 3
  GRB2 associated binding protein 3
  keratin associated protein 10-8
  keratin associated protein 1-1
  major histocompatibility complex, class I, B
  microtubule associated scaffold protein 2
  notch 2 N-terminal like A
  small glutamine rich tetratricopeptide repeat containing alpha
  Src like adaptor 2
  suppressor of cytokine signaling 1
  SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a, member 4
  tripartite motif containing 25
  tumor necrosis factor
  vir like m6A methyltransferase associated

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.