AMD1, adenosylmethionine decarboxylase 1

AMD1, adenosylmethionine decarboxylase 1

• This gene encodes an important intermediate enzyme in polyamine biosynthesis. The polyamines spermine, spermidine, and putrescine are low-molecular-weight aliphatic amines essential for cellular proliferation and tumor promotion. Multiple alternatively spliced transcript variants have been identified. Pseudogenes of this gene are found on chromosomes 5, 6, 10, X and Y. [provided by RefSeq, Dec 2013]

• Gene Synonyms (S-adenosylmethionine decarboxylase proenzyme, S-adenosylmethionine decarboxylase 1, ADOMETDC, AMD, SAMDC,)
• NCBI Gene ID: 262
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q5VXN5
  UNIPROT ID#>>Q6N0B2
  UNIPROT ID#>>P17707
  UNIPROT ID#>>A0A088AWN0
  UNIPROT ID#>>B4DZ60
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

adenosylmethionine decarboxylase 1 interacts with:

• adenosylmethionine decarboxylase 1
  astacin like metalloendopeptidase
  bone morphogenetic protein 15
  bone morphogenetic protein 7
  coiled-coil domain containing 120
  C-type lectin domain containing 11A
  deoxyribonuclease 2 beta
  dickkopf like acrosomal protein 1
  docking protein 3
  ELAV like RNA binding protein 1
  F-box protein 4
  glycolipid transfer protein
  heat shock protein family B (small) member 1
  heterogeneous nuclear ribonucleoprotein L
  histone deacetylase 11
  kaptin, actin binding protein
  mediator complex subunit 4
  mitotic spindle positioning
  nyctalopin
  parathyroid hormone 2
  POP4 homolog, ribonuclease P/MRP subunit
  proline and arginine rich end leucine rich repeat protein
  proopiomelanocortin
  retbindin
  RNA polymerase II subunit M
  SHC adaptor protein 1
  SHC adaptor protein 4
  sorting nexin family member 21
  SSX family member 2
  THAP domain containing 4
  transcription factor 25

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.