DLX2, distal-less homeobox 2

DLX2, distal-less homeobox 2

• Many vertebrate homeo box-containing genes have been identified on the basis of their sequence similarity with Drosophila developmental genes. Members of the Dlx gene family contain a homeobox that is related to that of Distal-less (Dll), a gene expressed in the head and limbs of the developing fruit fly. The Distal-less (Dlx) family of genes comprises at least 6 different members, DLX1-DLX6. The DLX proteins are postulated to play a role in forebrain and craniofacial development. This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 2. [provided by RefSeq, Jul 2008]

• Gene Synonyms (homeobox protein DLX-2, distal-less homeo box 2, TES-1, TES1,)
• NCBI Gene ID: 1746
• Species: Homo sapiens (Human)
• UNIPROT ID#>>Q53QU7
  UNIPROT ID#>>Q07687
  UNIPROT ID#>>X5D7D8
• View the NCBI Database for this Gene »

Gene products are often involved in multiple pathways and networks within a living cell. Learn more about other interacting partners.

distal-less homeobox 2 interacts with:

• DiGeorge syndrome critical region gene 6
  disco interacting protein 2 homolog A
  distal-less homeobox 2
  distal-less homeobox 5
  granulin precursor
  homeobox C8
  major vault protein
  msh homeobox 1
  msh homeobox 2
  nuclear receptor coactivator 2
  parkin RBR E3 ubiquitin protein ligase
  phosphoinositide-3-kinase regulatory subunit 1
  TSPO associated protein 1
  X-ray repair cross complementing 6

Paste a protein or nucleic acid sequence in the box below to confirm that it matches this gene’s reference sequence(s). Click on a link under RELATED ORF CLONES to see how a sequence matches to an experimentally-validated ORF clone.