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Promega Corporation

Reporter Assays

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NanoLuc luciferase reporters for gene regulation studies
Small, Bright and Versatile

The small size and bright luminescence of NanoLuc® Luciferase bring unparalleled sensitivity to reporter assays. This versatile luciferase allows sensitive detection at low expression levels, bringing the advantages of bioluminescent detection to applications such as protein interactions, BRET assays, imaging, and more.

Featured Products

Nano-Glo® Luciferase Assay System

This one-step assay will detect NanoLuc® Luciferase, an all new, state-of-the-art technology offering unrivaled sensitivity and versatility in a very small reporter.

ONE-Glo™ + Tox Luciferase Reporter and Cell Viability Assay

The ONE-Glo™ + Tox Assay combines luciferase assay chemistry with a cell viability marker to better understand reporter gene expression in the context of cell health.

Dual-Luciferase® Reporter Assay System

This non-homogeneous reagent system is the most sensitive method for quantifying cotransfected firefly and Renilla luciferases.

Renilla-Glo® Luciferase Assay System

This single reagent offers mix-and-read simplicity to a Renilla luciferase reporter system. The glow-type signal provides low background for improved sensitivity over an extended period of time.

Bright-Glo™ Luciferase Assay System

This assay offers the brightest, most sensitive option for mix-and-read detection of firefly luciferase. It is compatible with high-throughput formats, especially when used in a continuous process format.

Dual-Glo™ Luciferase Assay System

This homogeneous reagent system offers fast and simple quantitation of cotransfected  firefly and Renilla luciferase activities.

Featured Resources

pubhub_fr Reporter Assays and More: Applications of NanoLuc® Luciferase

An article describing how NanoLuc® Luciferase is used to monitor protein stability, detect protein interactions, and image events in cells and whole animals.

Multimedia_fr Introduction to Reporter Gene Assays

This animation introduces the concept of reporter gene assays, using the Dual-Luciferase® Assay as a model.

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