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Promega Corporation

ZAK Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant full-length human ZAK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. ZAK is a member of the MAPKKK family of signal transduction molecules and mediates gamma radiation signaling leading to cell cycle arrest. The activity of ZAK plays a role in cell cycle checkpoint regulation as well as being involved in regulating actin organization (1). Expression of kinase-dead ZAK in mouse fibroblasts disrupts actin stress fibers and causes morphologic changes. ZAK can activate JNK through MKK4/MKK7 and ERK5/p38-gamma via MKK3/MKK6. Expression of ZAK increa...

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ZAK Kinase Enzyme System
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ZAK Kinase Enzyme System  Components

10μg
- V4244 $ 406.00 Add to cart

ZAK Kinase Enzyme System

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ZAK Kinase Enzyme System

 Components

1mg
- V6571 $ 5,990.00 Add to cart
ADP-Glo™ Kinase Assay + ZAK Kinase Enzyme System
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ADP-Glo™ Kinase Assay + ZAK Kinase Enzyme System  Components

  • ZAK Kinase Enzyme System

    V42441 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V4245 $ 808.00 Add to cart


Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

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