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Promega Corporation

TOPK Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant full-length human TOPK was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. TOPK is a MAPK kinase that phosphorylates p38 MAPK and is activated in a cell-cycle-dependent manner in neuronal progenitor cells in vitro (1). Expression of TOPK is detected in male germ line progenitor cells, activated T-cells and a variety of lymphomas and leukemias. In vitro studies have shown that activated TOPK phosphorylates p38 MAPK but not JNK or ERK. TOPK activation requires phosphorylation by both the M-phase CDK1/CyclinB kinase complex and another unknown kin...

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TOPK Kinase Enzyme System
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TOPK Kinase Enzyme System  Components

10μg
- V4094 $ 406.00 Add to cart

TOPK Kinase Enzyme System

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TOPK Kinase Enzyme System

 Components

1mg
- V6568 $ 5,990.00 Add to cart
ADP-Glo™ Kinase Assay + TOPK Kinase Enzyme System
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ADP-Glo™ Kinase Assay + TOPK Kinase Enzyme System  Components

  • TOPK Kinase Enzyme System

    V40941 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V4095 $ 808.00 Add to cart


Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

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