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Promega Corporation

PAK1/CDC42 Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant full-length human PAK1 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag and combined with CDC42 at a ratio of 1:4 (PAK1:CDC42) in vitro. PAK1 is a member of the p21-activated kinases (PAKs), which have been implicated in the regulation of cell morphology, motility and transformation. These serine/threonine kinases are activated by and are effectors of small GTPases, CDC42 and RAC. PAK1 is one of the Group I PAKs, which also include PAK2 and PAK3 (1). PAK1 is a key regulator of the actin cytoskeleton, adhesion and cell motility. Inactive dimeric PA...

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Product Size Conc. Catalog # *List Price Order QTY Add to Cart
PAK1/CDC42 Kinase Enzyme System
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PAK1/CDC42 Kinase Enzyme System  Components

10μg
- V4478 $ 406.00 Add to cart

PAK1/CDC42 Kinase Enzyme System

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PAK1/CDC42 Kinase Enzyme System

 Components

1mg
- V6457 $ 5,990.00 Add to cart
ADP-Glo™ Kinase Assay + PAK1/CDC42 Kinase Enzyme System
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ADP-Glo™ Kinase Assay + PAK1/CDC42 Kinase Enzyme System  Components

  • PAK1/CDC42 Kinase Enzyme System

    V44781 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V4479 $ 808.00 Add to cart


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Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

V4478, V6457, V4479 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

V4479 U.S. Pat. Nos. 7,083,911, 7,452,663 and 7,732,128 and other patents.

V4479 U.S. Pat. No. 7,700,310 and other patents and patents pending.

V4479 U.S. Pat. No. 7,741,067 and other patents and patents pending.

V4479 U.S. Pat. Nos. 6,602,677, 7,241,584 and 8,030,017 and other patents and patents pending.

V4479 U.S. Pat. No. 8,183,007 and other patents pending.

V4479 Licensed from Lonza Nottingham Ltd. under U.S. Pat. Nos. 6,599,711 and 6,911,319 and other pending and issued patents.

V4479 The method of recombinant expression of Coleoptera luciferase is covered by U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673.

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