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Promega Corporation

BTK Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant full-length human BTK was expressed by baculovirus in Sf9 insect cells using an N-terminal His tag. BTK (also known as Bruton tyrosine kinase) plays a crucial role in B-lymphocyte differentiation and activation. BTK interacts with SRC homology 3 domains of FYN, LYN and HCK that are activated upon stimulation of B- and T-cell receptors. Defects in the BTK gene cause Agammaglobulinemia, an X-linked immunodeficiency characterized by failure to produce mature B lymphocyte cells and associated with a failure of Ig heavy chain rearrangement. The unique role of BTK makes it a de...

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Product Size Conc. Catalog # *List Price Order QTY Add to Cart

BTK Kinase Enzyme System

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BTK Kinase Enzyme System

 Components

10μg
- V2941 $ 406.00 Add to cart

BTK Kinase Enzyme System

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BTK Kinase Enzyme System

 Components

1mg
- V2942 $ 5,990.00 Add to cart

ADP-Glo™ Kinase Assay + BTK Kinase Enzyme System

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ADP-Glo™ Kinase Assay + BTK Kinase Enzyme System

 Components

  • BTK Kinase Enzyme System

    V29411 x 10μg
  • ADP-Glo™ Kinase Assay

    V91011 x 1,000 assays
1 each
- V9071 $ 808.00 Add to cart


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Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

Use Restrictions

V2941, V2942, V9071 For Research Use Only. Not for Use in Diagnostic Procedures.

Patents - Disclaimers

V9071 U.S. Pat. Nos. 7,083,911, 7,452,663 and 7,732,128 and other patents.

V9071 U.S. Pat. No. 7,700,310 and other patents and patents pending.

V9071 U.S. Pat. No. 7,741,067 and other patents and patents pending.

V9071 U.S. Pat. Nos. 6,602,677, 7,241,584 and 8,030,017 and other patents and patents pending.

V9071 U.S. Pat. No. 8,183,007 and other patents pending.

V9071 Licensed from Lonza Nottingham Ltd. under U.S. Pat. Nos. 6,599,711 and 6,911,319 and other pending and issued patents.

V9071 The method of recombinant expression of Coleoptera luciferase is covered by U.S. Pat. Nos. 5,583,024, 5,674,713 and 5,700,673.

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