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Promega Corporation

CHK2 Kinase Enzyme System

See All Kinase Enzyme Systems
Recombinant full-length human CHK2 was expressed by baculovirus in Sf9 insect cells using an N-terminal GST tag. CHK2 is rapidly phosphorylated and activated in response to replication blocks and DNA damage; the response to DNA damage occurs in an ataxia telangiectasia mutated (ATM)-dependent manner (1). Expression of wild-type CHK2 leads to increased p53 stabilization after DNA damage, whereas expression of a dominant-negative CHK2 mutant abrogated both phosphorylation of p53 on Ser-20 and p53 stabilization (2).

ADP-Glo™ Kinase Assay is a luminescent kinase assay that measures A...

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  • Prices valid for US customers only
Product Size Conc. Catalog # *List Price QTY Add to Cart
CHK2 Kinase Enzyme System 10μg
- V4020 $ 406.00 Add to cart

CHK2 Kinase Enzyme System

1mg
- V6284 $ 5,990.00 Add to cart
ADP-Glo™ Kinase Assay + CHK2 Kinase Enzyme System 1 each
- V4021 $ 808.00 Add to cart


Storage Conditions

Upon receipt, centrifuge the kinase and dispense it into smaller quantities. Store the kinase at –70°C and the rest of the components at –20°C.

For product intended use please see Patents & Disclaimers tab.

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